The multivariate Wright–Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model
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چکیده
منابع مشابه
The multivariate Wright-Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model.
We consider the diffusion approximation of the multivariate Wright-Fisher process with mutation. Analytically tractable formulas for the first-and second-order moments of the allele frequency distribution are derived, and the moments are subsequently used to better understand key population genetics parameters and modeling frameworks. In particular we investigate the behavior of the expected ho...
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ژورنال
عنوان ژورنال: Theoretical Population Biology
سال: 2016
ISSN: 0040-5809
DOI: 10.1016/j.tpb.2015.11.001